Study of Non-Specific Symptoms of Gastro Esophageal Reflux Disease: A Population-based Study
DOI:
https://doi.org/10.22100/jkh.v4i2.175Keywords:
Non-Specific symptoms, Reflux, Dispenea, Cough, Iran.Abstract
Introduction: Gastro esophageal reflux disease (GERD) is a common gastrointestinal disorder all over the world. Some patients with GERD have no symptoms while others may have non-specific symptoms. The aim of this study was to define the frequency of non- specific symptoms of gastro esophageal reflux and to determine the association of these symptoms with GERD in a population- based study.
Methods: This cross-sectional and population- based study was conducted on 782 subjects who were randomly selected from 2 cities of Firoozkooh and Damavand in the northeast of Tehran province. The relationship between non-specific symptoms and GERD was assessed through Chi-square and the odds ratios (OR) with 95% of certainty levels were calculated for each symptom.
Results: In this study, 228 persons (29.2%) with GERD were diagnosed. The most common non-specific symptom in the subjects was abdominal pain with a distinct female preponderance. Globus sensation, cough and dyspnea, and halitosis were among the other symptoms having a direct relationship with GERD. No significant relationship was observed between age and non-specific symptoms of GERD.
Conclusion: In sum, this study showed the prevalence of non-specific symptoms which are strongly related to gastro esophageal reflux disease. Therefore, considering these symptoms in diagnosis course of the disease seems necessary.
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