Evaluation of Mongolian Spots Prevalence and Its Related Factors in Neonates in Tehran
DOI:
https://doi.org/10.22100/jkh.v4i4.194Keywords:
Mongolian spots, Prevalence, Common sites.Abstract
Introduction: Mongolian spots (Congenital Dermal Melanocytosis) are the most frequently encountered pigmented lesions in newborns. The spots typically appear as congenital blue-grey macules. These lesions vary in size and color. The most common location is the sacro-gluteal area. Its prevalence varies from 10% in Caucasians to more than 90% in Mongolians. Only a limited number of studies were carried out to investigate the frequency of these spots in Iran. This study was conducted to study Mongolian spots prevalence and their common sites in newborns at Lolagar hospital
Methods: This descriptive-Analytic study was carried out for two years (2004-2006) at Lolagar hospital in Tehran. During this period, 1706 newborns were examined by pediatricians for Mongolian spots prevalence and their common sites in newborns.
Results: Mongolian spots were observed in 37.3% (637 Neonates) neonates. The most frequent site of involvement was the sacral, followed by the gluteal area. Mongolian spots prevalence did not show any significant statistical relationship to sex, gestational age, mother’s age, birth weight and delivery type (P>0.05).
Conclusion: The prevalence of Mongolian spots at Lolagar hospital was similar to the prevalence reported in previous studies in Tehran and Yazd. However it was different from the prevalence reported in studies done in Ahvaz and Bosher. A complementary genealogical study on a representative Iranian sample is necessary.
References
Snow TM. Mongolian spots in the newborn: do they mean anything?. Neonatal Netw 2005;24(1):31-33.
Leung AK, Kao CP, Leung AA. Persistent mongolian spots in Chinese adults. Int J Dermatol 2005;44(1):43-45.
Leung AK, Kao CP, Lee TK. Mongolian spots with involvement of the temporal area. Int J Dermatol 2001;40(4):288-289.
Jacobs AH, Walton RG. The incidence of birthmarks in the neonate. Pediatrics 1976;58(2):218-222.
Torrelo A, Zambrano A, Happle R. Large aberrant mongolian spots coexisting with cutis marmorata telangiectatica congenita (phacomatosis pigmentovascularis type V or phacomatosis cesiomarmorata). J Eur Acad Dermatol Venereol 2006;20(3):308-310.
Ochiai T, Ito K, Okada T, Chin M, Shichino H, Mugishima H. Significance of extensive mongolian spots in Hunter's syndrome. Br J Dermatol 2003;148(6):1173-1178.
Leung AK, Robson WL. Mongolian spots and GM1 gangliosidosis type one. J R Soc Med 1993;86(2):120-121.
Cordova A. The Mongolian spot: a study of ethnic differences and a literature review. Clin Pediatr 1981;20(11):714-719.
Leung AK, Kao CP. Extensive mongolian spots with involvement of the scalp. Pediatr Dermatol 1999;16(5):371-372.
Smith M, Schofield OMV. An infant presenting with skin colour changes. Clin Exp Dermatol 2005;30(3);313–315.
Torrelo A, Zambrano A, Happle R. Cutis marmorata telangiectatica congenita and extensive mongolian spots: type 5 phacomatosis pigmentovascularis. Br J Dermatol 2003;148(2):342-345.
Ashrafi MR, Shabanian R, Mohammadi M, Kavusi S. Extensive Mongolian spots: a clinical sign merits special attention. Pediatr Neurol 2006;34(2):143-145.
Ortonne JP, Floret D, Coiffet J, Cottin X .Ocular and cutaneous melanosis associated with the Sturge-Weber syndrome: clinical, histological, and ultrastructural studies of one case. Ann Dermatol Venereol 1978;105(12):1019-1031.
Silengo M, Battistoni G, Spada M. Is there a relationship between extensive mongolian spots and inborn errors of metabolism?. Am J Med Genet 1999;87(3):276-277.
Kawara S, Takata M, Hirone T, Tomita K, Hamaoka H. A new variety of neurocutaneous melanosis: benign leptomeningeal melanocytoma associated with extensive Mongolian spot on the back. Nippon Hifuka Gakkai Zasshi 1989;99(5):561-566.
Camur S, Coskun T, Kiper N. Alpha-mannosidosis: the first Turkish case. Acta Paediatr Jpn 1995;37(2):230-232.
Schwartz RA, Cohen-Addad N, Lambert MW, Lambert WC. Congenital melanocytosis with myelomeningocele and hydrocephalus. Cutis 1986;37(1):37-39.
Valizadeh Gh. Prevalence of Mongolian spots in Iranian neonates. Med System J 1976;4(4):352.[Persian].
Mirjalili A, Dabestani Tafti T. Prevalence of skin manifestations of Erythema toxicom, Milia and Mongolian spots in neonates of Afshar and Bahman hospitals of Yazd. [Dissertation]: Shahid Sadooghi Univ.;1995[Persian].
Moosavi Z, Hosseini T. One-year survey of cutaneous lesions in 1000 consecutive Iranian newborns. Pediatr Dermatol 2006;23(1):61–63.
Pouladfar Gh, Malahzadeh AR. The prevalence of minor congenital anomalies and normal variations in neonates in bushehr port. Iranian South Medical Journal 2005;8(1):43-52.[Persian].
Hidano A, Purwoko R, Jitsukawa. Statistical survey of skin changes in Japanese neonates. Pediatr Dermatol 1986;3(2):140-144.
Nanda A, Kaur S, Bhakoo ON, Dhall K .Survey of cutaneous lesions in Indian newborns. Pediatr Dermatol 1989;6(1):39-42.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
