Assessment of Antioxidant Capacity and Anti-Inflammatory of Alcoholic Extraction of Chamomile, Morus, Marshmallow, Borage and Rosemary

Authors

  • Parisa Sadighara دانشگاه علوم پزشکی تهران- دانشکده بهداشت- دپارتمان بهداشت محیط- بخش مواد غذایی
  • Abbas Barin دانشگاه تهران- دانشکده دامپزشکی- دپارتمان کلینیکال پاتولوژی
  • Gholmreza Jahed دانشگاه علوم پزشکی تهران- دانشکده بهداشت- دپارتمان بهداشت محیط- بخش مواد غذایی
  • Fateme Farjadmand وزارت بهداشت و درمان و آموزش پزشکی- سازمان غذا و دارو

DOI:

https://doi.org/10.22100/jkh.v8i1.41

Keywords:

Antioxidant capacity, Anti-inflammatory effects, Medicine plants

Abstract

Introduction: In recent years, there has been a growing interest in finding new compound with herbal origins for treatment and prevention of disease. This study aims at investigating the antioxidant and anti-inflammatory activity of Borage officinalis, althaea officinalis, chamaemelum nobile, morus alba and rosmarinus officinals which are commonly used in traditional medicine.

Methods: In this study the antioxidant activity was investigated by applying cupric ion reducing assay (cupric assay) and anti-inflammatory activity investigated through inhibition albumin serum denaturation.

Results: Morus alba, chamaemelum nobile and borage officinals were found to have the highest antioxidant capacity. Chamaemelum nobile, rosmarinus officinals and althaea officinalis had considerable anti-inflammatory activity and the alcoholic extraction of nobile and rosmarinus officinals had marked anti-inflammatory and antioxidant effects.

Conclusion: Use of screening tests such as the above-mentioned methods are useful for finding biological components with different effects.

References

Asghari S, Naderi GH, Bashardoost N, Etminan Z. The study of antioxidant potential of chamaemelum nobile extract on liver cell of rats. Journal of Herbal Drugs 2011;1:69-76.

Koksal E, Gulcin I. Antioxidant activity of cauliflower. Turk J Agric 2008;32:65-78.

Kahkonen M, Hopia AI, Vuorela HJ, Rauha JP, Pihlaja K, Kujla TS, et al. Antioxidant activity of plant extracts containing phenolic compounds. J Agric Food Chem 1999;47:3954-3962.

Anilkumar M. 10 ethnomedicinal plants as anti-inflammatory and analgesic agents. Ethnomedicine 2010;2:267-293.

Palasuwan A, Soogarun S, Lertlum T, Pradniwat P, Wiwanitkit V. Inhibition of heinz body induction in an in vitro model and total antioxidant activity of medicinal thai plants. Asian Pacific J Cancer Prev 2006;6:458-463.

Apak R, Guclu K, Ozyurek M, Celik SE. Mechanism of antioxidant capacity assays and the CUPRAC assay. Microchimica Acta 2008;160:413-419.

Sakat S, Juvekar AR, Gambhire MN. In vitro antioxidant and anti-inflammatory activity of methanol extract of oxalis corniculata Linn. I J Pharm Sci 2010;2:146-155.

Sadighara P, Barin A. The study of antioxidant potential of morus alba L. leaves extract. Journal of Herbal Drugs 2010;3:43-46.

Govindappa M, Sadananda TS, Channabasava R, Raghavendra V. In vitro anti-inflammatory, lipoxygenase, xanthine oxidase and acetycholinesterase inhibitory activity of Tecoma Stans. International Journal of Pharma and Biosciences 2011;2:275-283.

Cioanca O, Miron A, Aprotosoaie AC, Hancianu M, Trifan A, Stanescu U. Contributions to the comparative study of the antioxidant potential of some extracts obtained from chamomile flowers. Rev Med Chir Soc Med Nat Iasi 2009;113:1274-9.

Graf MD. Herbal anti-inflammatory agents for skin disease. Skin Therapy Letter 2000;5:3-5.

Aberer W. Contact allergy and medicinal herbs. J Dtsch Dermatol Ges 2008;6:15-24.

Hara M, Kiefer D, Farrell K, Kemper K. A review of 12 commonly used medicinal herbs. Arch Fam Med 1998;7:523-536.

Altinier G, Sosa S, Aquino RP, Mencherini T, Della Loggia R, Tubaro A. Characterization of topical antiinflammatory Compounds in rosmarinus officinalis L. J Agric Food Chem 2007; 55(5):1718-1723.

Ciriano MG, García-Herreros C, Larequi E, Valencia I, Ansorena D, Astiasarán I. Use of natural antioxidants from lyophilized water extracts of Borago officinalis in dry fermented sausages enriched in omega-3 PUFA. Meat Sci 2009;83:271-277.

Abdel-moein NM, Mohamed DA, Hanfy EA. Evaluation of the anti-inflammatory and anti-arthritic of some plant extracts. International Journal of Fats and Oils 2011;62:365-374.

Leelaprakash G, MohanDass S. In vitro anti_inflammatory activity of methanol extract of enicostemma axllare. International Journal of Drug Development & Research 2010;3:189-196.

Published

2013-01-22

Issue

Section

Original Article(s)

How to Cite

Assessment of Antioxidant Capacity and Anti-Inflammatory of Alcoholic Extraction of Chamomile, Morus, Marshmallow, Borage and Rosemary. (2013). Knowledge and Health in Basic Medical Sciences, 8(1), 31-34. https://doi.org/10.22100/jkh.v8i1.41

Most read articles by the same author(s)