The Effect of Varicocelectomy on Spermatogram Index

Authors

  • Mohammad Bagher Sohrabi
  • Aminollah Amini
  • Pooneh Zolfaghari
  • Elahe Yahyaei

DOI:

https://doi.org/10.22100/jkh.v9i2.395

Keywords:

Varicocele, Varicocelectomy, Sperm analyzed index.

Abstract

Introduction: Varicocele is a common cause of male infertility that is treatable, and often its diagnosis is delayed due to various factors. Because of high prevalence of varicocele in men, the diagnosis and treatment of this problem have always been parts of important steps in urology. Several studies have been conducted on the treatment of varicocele and semen quality changes that were usually incomplete and had different results.

Method: This cross-sectional study was performed on all patients who were diagnosed with varicocele since 2009 till 2011. After completion of self-reported questionnaire for each patient, examination of semen fluid were carried out before and after varicocelectomy (twice in three months and six months after varicocelectomy) and the results were compared.

Result: In this study, mean age of 250 individuals was 35.2 ± 3.9 years. The majority of the subjects were in the age group 31-40 years (70.8 %). 198 cases (79.2%) of the total patients were married. In 218 cases (87.2%), varicoceles were in left side. This research showed that surgical treatment caused the better semen index including mean volume semen (P<0.001), mean count sperm (P<0.001), motility of sperm (P<0.001), morphology of sperm (P<0.001) and mean pH (P<0.001).

Conclusion: This research shows that timely diagnosis and treatment of varicocele can improve the sperm quality index and probably decrease the men infertility.

References

Evers JH, Collins J, Clarke J. Surgery or embolization for varicocelles in sub fertile men. Cochrane Database Syst Rev 2012;21(1):342-7.

Zorba UO, Sanli OM, Tezer M, Erdemir F, Shavakhabov S, Kadioqlu A. Effect of infertility duration on postvaricocelectomy sperm counts and pregnancy rates. Urology 2009;73(4):767-71.

Vujkovic M, de Vries JH, Dohle GR, Bonsel GJ, Lindemans J, Macklon NS, et al. Associations between dietary patterns and semen quality in men undergoing IVF/ICSI treatment. Hum Reprod 2009;24(6):1304-12.

Mancini A, Festa R, Silvestrini A, Nicolotti N, Di Donna V, La Torre G, et al. Hormonal regulation of total antioxidant capacity in seminal plasma. J Androl 2009;30(5):534-40.

Mostafa T, Anis T, Imam H, El-Nashar AR, Osman IA. Seminal reactive oxygen species-antioxidant relationship in fertile males with and without varicocele. Andrologia 2010;41(2):125-9.

Baazeem A, Boman JM, Libman J, Jarvi K, Zini A. Microsurgical varicocellectomy for infertile men with oligospermia: differential effect of bilateral and unilateral varicocelle on pregnancy outcomes. BJU Int 2009;104(4):524-8.

Acar H, Kilinc M, Guven S, Yurdakul T, Celik R. Comparison of semen profile and frequency of chromosome aneuploidies in sperm nuclei of patients with varicocelle before and after varicocellectomy. Andrologia 2012;41(3):157-62.

Biyani CS, Cartledge J, Janetschek G. Varicocelle. Clin Evid (Online) 2009.p.1806.

Youssef T, Abd-Elaal E, Gaballah G, Elhanbly S, Eldosoky E. Varicocelectomy in men with nonobstructive azoospermia: is it beneficial?. Int J Surg 2012;7(4):356-60.

Chen XF, Zhou LX, Liu YD, Ping P, Chen YH, Cao M, et al. Comparative analysis of three different surgical approaches to varicocelectomy. Zhonghua Nan Ke Xue 2010;15(5):413-6.

Makker K, Agarwal A, Sharma R. Oxidative stress & male infertility. Indian J Med Res 2012;129(4):357-67.

Hu Y, Xia XY, Pan LJ, Lü NQ, Wu YM, Zhou X, et al. Evaluation of sperm mitochondrial membrane potential in varicocele patients using JC-1 fluorescent staining. Zhonghua Nan Ke Xue 2009;15(9):792-5.

Caretta N, Palego P, Schipilliti M, Torino M, Pati M, Ferlin A, et al. Testicular contrast harmonic imaging to evaluate intratesticular perfusion alterations in patients with varicocele. J Urol 2010;183(1):263-9.

Smith M, Romijn JC, Wildhagen MF, Veldhoven JL, Weber RF, Dohle GR. decreased sperm dna fragmentation after surgical varicocelectomy is associated with increased pregnancy rate. J Urol 2010;183(1):270-4.

Rodriguez Peña M, Alescio L, Russell A, Lourenco da Cunha J, Alzu G, Bardineschi E. Predictors of improved seminal parameters and fertility after varicocele repair in young adults. Andrologia 2009;41(5):277-81.

Shamsa A, Mohammadi L, Abolbashari M, Shakeri MT, Shamsa S. Comparison of open and laparoscopic varicocelectomies in terms of operative time, sperm parameters, and complications. Urol J 2009;6(3):170-5.

Collodel G, Capitani S, Iacoponi F, Federico MG, Pascarelli NA, Moretti E. Retrospective assessment of potential negative synergistic effects of varicocele and tobacco use on ultrastructural sperm morphology. Urology 2009;74(4):794-9.

Salem HK, Mostafa T. Preserved testicular artery at varicocelle repair. Andrologia 2012;41(4):241-5.

Basar MM, Kisa U, Tuglu D, Kacmaz M, Basar H. The effect of varicocelle on seminal plasma and serum inhibin-B levels in adolescent and adult men. Int Urol Nephrol 2011;10(4):286-6.

Saxena P, Misro MM, Roy S, Chopra K, Sinha D, Nandan D, et al. Possible role of male factors in recurrent pregnancy loss. Indian J Physiol Pharmacol 2008;52(3):274-82.

Published

2014-03-20

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How to Cite

The Effect of Varicocelectomy on Spermatogram Index. (2014). Knowledge and Health in Basic Medical Sciences, 9(2), Page:47-51. https://doi.org/10.22100/jkh.v9i2.395

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