Quantitative Determination of Di (2-Ethylhexyl) Phthalate (DEHP) in Hemodialysis-Related Materials
DOI:
https://doi.org/10.22100/jkh.v7i2.98Keywords:
Di (2-ethylhexyl) phthalate, Catheters, HemodialysisAbstract
Introduction: Phthalates are founded in medical devices such as filters and dialysis catheters. Scientific evidences show health disadvantages due to exposure to phthalates. In this study, level of Di (2-ethylhexyl) phthalate (DEHP) in Iranian hemodialysis-related materials was measured.
Methods: Ten samples of Iranian dialysis catheters (five samples from SUPA medical devices company (SUPA-MDC) and five samples from Helal Ahmar- MDC) were randomly selected. The level of DEHP for each sample was measured by Gas chromatography- Mass spectrometry (GC-MS). Mean concentrations of DEHP (mg per ml) for each brand was reported separately.
Results: Means of DEHP concentration for SUPA- MDC and Helal Ahmar- MDC were 1.36±0.11 and 0.97±0.11 mg/ml, respectively. Range of measured concentrations differed from 1.47 to 1.21 mg/ml and 1.13 to 0.83 mg/ml, for SUPA- and Helal Ahmar-MDCs respectively.
Conclusion: Application of alternative medical products without or with less phthalate could reduce exposure of patients to phthalates.References
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