Evaluation of serum antibody against Chlamydia pneumonia infection in patients with Chronic obstructive pulmonary disease in Tabriz hospitals
Authors
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Abolfazl Jafari-Sales1
1- Dept. of Microbiology School of Basic Sciences, Kazerun Branch, Islamic Azad University, Kazerun, Iran.
http://orcid.org/0000-0002-5710-4076
- Yashar Bagherizadeh 1
- Raziyeh Helali-Pargali 1
- Masood Khalifehpour 1
- Nazila Imeni 2 2- Young Researchers and Elite Clube, Marand Branch, Islamic Azad University, Marand, Iran.
- Behboud Jafari 3 3- Dept. of Microbiology, Ahar Branch, Islamic Azad University, Ahar, Iran.
DOI:
https://doi.org/10.22100/jkh.v13i4.2071Keywords:
Chronic obstructive pulmonary disease, Chlamydia pneumonia, AntibodyAbstract
Introduction: Chronic obstructive pulmonary disease (COPD) is the most common cause of death and disability due to pulmonary disease, in Which microbial agents has a significant role. Regarding the role of Chlamydia pneumonia infection in the initiation and development of COPD, this study aimed to evaluate the serum antibody level against C.pneumonia infection in patients with COPD in Tabriz hospitals in 2017.
Methods: In this descriptive cross-sectional study, 200 patients with COPD participated. Anti C.pneumoniae titers were determined by ELISA method. Statistical analysis was performed using SPSS software and T-test.
Results: The mean IgG antibody was 73.94% and the mean IgM antibody was 0.955%. There was no association between sex with antibody level, smoker status, coronary artery stenosis, and anti-infectious antibodies to C.pneumoniae.
Conclusion: According to the results, although there was no significant correlation between C.pneumonia infection and COPD, However, due to the importance of C.pneumoniae as a causative pathogen, it is recommended to use more specific methods, such as determining the presence of the bacterial genome in the case and control groups.
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