خواص درمانی و کاربردی گیاه خرنوب: از دستورات طب سنتی تا یافته‌های جدید

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Mehraban Z, Novin MG, Golmohammadi MG, Nazarian H. Effect of Ceratonia siliqua L. extract on DNA Fragmentation of Sperm in Adult Male Mice Treated with Cyclophosphamide. Reprod Sci 2021;28:974-81. doi: 10.1007/s43032-020-00322-3

Aghajani MMR, Mahjoub S, Mojab F, Namdari M, Gorji NM, Dashtaki A, et al. Comparison of the Effect of Ceratonia Siliqua L.(Carob) Syrup and Vitamin E on Sperm Parameters, Oxidative Stress Index, and Sex Hormones in Infertile Men: A Randomized Controlled Trial. Reprod Sci 2021;28:766-74. doi: 10.1007/s43032-020-00314-3

Vafaei A, Mohammadi S, Fazel A, Soukhtanloo M, Mohammadipour A, Beheshti F. Effects of carob (Ceratonia siliqua) on sperm quality, testicular structure, testosterone level and oxidative stress in busulfan-induced infertile mice. Pharm Sci 2018;24:104-11. doi: 85049312066

Faramarzi A, Aghaz F, Jahromi MG, Bakhtiari M, Khazaei M. Does supplementation of sperm freezing/thawing media with Ceratonia siliqua improve detrimental effect of cryopreservation on sperm parameters and chromatin quality in normozoospermic specimens? Cell Tissue Bank 2019;20:403-9. doi: 10.1007/s10561-019-09779-2

Faramarzi A, Aghaz F, Bakhtiari M, Khazaei M. In vitro application of Ceratonia siliqua improved sperm parameters and chromatin quality after vitrifacation in normozoospermic aged men. Middle East Fertil Soc J 2020;24:1-5. doi: 10.1186/s43043-019-0007-9

Faramarzi A, Aghaz F, Bakhtiari M, Roshankhah S, Rashidi Z, Khazaei M. Ceratonia siliqua (Carob) extract improved in vitro development of vitrified-warmed mouse germinal vesicle oocytes: assessment of possible mechanism. Cell Tissue Bank 2021;22:137-44. doi: 10.1007/s10561-020-09873-w

Ammari M, Othman H, Rtibi K, Sakly M, Abdelmelek H. The Effects of Carob (Ceratonia siliqua L.) on Emotional Behavior Impairment and Metabolic Disorders Induced by Estrogen Deficiency in Rats. J Med Food 2020;23:961-6. doi: 10.1089/jmf.2019.0187

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Meziani S, Oomah BD, Zaidi F, Simon-Levert A, Bertrand C, Zaidi-Yahiaoui R. Antibacterial activity of carob (Ceratonia siliqua L.) extracts against phytopathogenic bacteria Pectobacterium atrosepticum. Microb Pathog 2015;78:95-102. doi: 10.1016/j.micpath.2014.12.001

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Saratsi K, Hoste H, Voutzourakis N, Tzanidakis N, Stefanakis A, Thamsborg SM, et al. Feeding of carob (Ceratonia siliqua) to sheep infected with gastrointestinal nematodes reduces faecal egg counts and worm fecundity. Vet Parasitol 2020;284:109200. doi: 10.1016/j.vetpar.2020.109200

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Lam EC, Li R, Rodrigues M, Vires L, Adams RL, Sherrill JD, et al. Enhanced retinoid response by a combination of the vitamin A ester retinyl propionate with niacinamide and a flavonoid containing Ceratonia siliqua extract in retinoid responsive in vitro models. Int J Cosmet Sci 2021;43:102-6. doi: 10.1111/ics.12669

Pekmezci E, Dündar C, Türkoğlu M. A proprietary herbal extract against hair loss in androgenetic alopecia and telogen effluvium: a placebo-controlled, single-blind, clinical-instrumental study. Acta Dermatovenerol Alp Pannonica Adriat 2018;27:51-7.

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Cavdarova M, Makris DP. Extraction kinetics of phenolics from carob (Ceratonia siliqua L.) kibbles using environmentally benign solvents. Waste Biomass Valori 2014;5:773-9. doi: 10.1007/s12649-014-9298-3

Gregoriou G, Neophytou CM, Vasincu A, Gregoriou Y, Hadjipakkou H, Pinakoulaki E, et al. Anti-Cancer Activity and Phenolic Content of Extracts Derived from Cypriot Carob (Ceratonia siliqua L.) Pods Using Different Solvents. Molecules 2021;19;26:5. doi: 10.3390/molecules26165017

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Martinez-Rodriguez R, Navarro-Alarcon M, Rodriguez-Martinez C, Fonolla-Joya J. Effects on the lipid profile in humans of a polyphenol-rich carob (Ceratonia siliqua L.) extract in a dairy matrix like a functional food; a pilot study. Nutr Hosp 2013;28:2107-14.

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Qasem MA, Noordin MI, Arya A, Alsalahi A, Jayash SN. Evaluation of the glycemic effect of Ceratonia siliqua pods (Carob) on a streptozotocin-nicotinamide induced diabetic rat model. Peer J 2018;6:e4788. doi: 10.7717/peerj.4788

Suzek H, Celik I, Dogan A. Nephroprotective hepatoprotective potential and antioxidant role of carob pods (Cerotonia siliqua L.) against carbon tetrachloride-induced toxicity in rats. Indian J Pharm Educ Res 2017;51:312-20. doi: 10.5530/ijper.51.2.37

Rtibi K, Jabri MA, Selmi S, Souli A, Sebai H, El-Benna J, et al. Gastroprotective effect of carob (Ceratonia siliqua L.) against ethanol-induced oxidative stress in rat. BMC Complement Altern Med 2015;15:1-8. doi: 10.1186/s12906-015-0819-9

Issaoui M, Flamini G, Delgado A. Sustainability Opportunities for Mediterranean Food Products through New Formulations Based on Carob Flour (Ceratonia siliqua L.). Sustainability 2021;13:8026. doi: 10.3390/su13148026

Rtibi K, Selmi S, Jabri M-A, El-Benna J, Amri M, Marzouki L, et al. Protective effect of Ceratonia siliqua L. against a dextran sulfate sodium-induced alterations in liver and kidney in rat. J Med Food 2016;19:882-9. doi: 10.1089/jmf.2016.0020

Navarro JA, Decara J, Medina-Vera D, Tovar R, Suarez J, Pavón J, et al. D-Pinitol from Ceratonia siliqua is an orally active natural inositol that reduces pancreas insulin secretion and increases circulating ghrelin levels in Wistar rats. Nutrients 2020;12:2030. doi: 10.3390/nu12072030