The Effect of Eight Weeks of Water Exercise with Supplementation Elaeagnus Angustifolia on Some Inflammatory and Growth Factors in Overweight Postmenopausal Women

Authors

DOI:

https://doi.org/10.22100/jkh.v18i1.2619

Abstract

Introduction: Menopause is a natural and inevitable component of women's lives and encompasses physiological, psychological, and social changes, including hot flashes, depression, muscle aches, inflammation, osteoporosis, and weight gain. Using herbal dietary supplements is an attractive approach to controlling obesity and associated complications. Therefore, this study aimed to investigate the effect of eight weeks of exercises in the water along with oleaster supplementation on C-reactive protein (CRP) and insulin-like growth factor-1 (IGF-1) in overweight and obese postmenopausal women.

Methods: Forty-two postmenopausal women with a mean age of 52.97± 5.08, mean weight 73.95± 8.09 kg and mean height 156.057±7.56 Cm randomly divided into four groups: control (n=10), exercise+ placebo (n=10), supplement (n=10), and exercise+ supplement (n=12). The exercise+ placebo group conducted eight weeks of water exercise with an intensity of 60-74% of maximum heart rate twice a week, the supplement group received daily supplementation of 15 g daily, the exercise+ supplement group eight weeks both used supplements and exercised in water and the control group did not undergo any exercise or supplements during eight weeks. Blood samples were collected from subjects in two stages to evaluate the variables under fasting conditions. CRP and IGF-1 concentrations in serum were measured using an ELISA kit and mass spectrometry, respectively.

Results: The results revealed a significant difference in C-reactive protein within the exercise+ supplement and supplement groups. Besides, there was a significant difference in insulin-like factor-1 among the three experimental groups (P<0.05).

Conclusion: The use of oleaster supplements and exercise in water has not been able to affect growth and inflammatory factors, so continuously taking oleaster supplements is not recommended for overweight postmenopausal women.

References

Haghighian Roudsari A, Tahbaz F, Arjmandi B, Larijani B, Kimiagar M. Effect of soy protein on bone markers in osteopenic menopause women. Journal of Reproduction & Infertility 2005;6. [Persian].

Askari F, Basiri MK, Basiri MM, Torabi S, Gholamfarkhani S, Mohareri M, Mirakhorlo S. Age of natural menopause and the comparison of incidence of its early complications in menopause transition stages in women from gonabad city. 2012.[Persian].

Shabani R. The effect of combined training on body composition, and ccoagulation and proinflammatory factors in overweight and obese postmenopausal women. Medical Sciences 2017;27:261-68. [Persian].

Cook D, Mendall M, Whincup P, Carey I, Ballam L, Morris J. C-reactive protein concentration in children: relationship to adiposity and other cardiovascular disease risk factors. Elsevier Inc, 2000;149:230-6. doi: 10.1016/s0021-9150(99)00312-3

Pearson A, Mensah G, Alexander R, Anderson J, Cannon R. Markers of inflammation and cardiovascular disease: application to clinical and public Health practice. American Heart Association. Circulation 2003;107:499-511. doi: 10.1161/01.cir.0000052939.59093.45

Pepys MB, Hirschfield GM. C-reactive protein: a critical update. The Journal of Clinical Investigation 2003;111:1805-12. doi: 10.1172/jci18921

Hosseini Kakhk AR, Amiri Parsa T, Azarnive M, Hamedinia MR. The effect of resistance training, aerobic training and detraining on the lipid profile and crp in obese girls. Journal of Sabzevar University of Medical Sciences 2011;18:188-97.[Persian].

Choobineh S, Dabidiroshan V, Gaeini A. The effect of aerobic continuous and intermittent training methods on HS-CRP in wistar rats. Journal of Motor Sciences and Sport 2007;5:1-13.[Persian].

Kelley GA, Kelley KS. Effects of aerobic exercise on creactive protein, body composition, and maximum oxygen consumption in adults: a meta – analysis of randomized controlled trials. Metabolism 2006;55:1500-7. doi: 10.1016/j.metabol.2006.06.021

Abbas Saremi, Nader Shavandi, Hajar Vafapour. Eight-week resistance training with vitamin D supplementation in postmenopausal women: Effects on skeletal muscle. Pajoohande 2013;18:57-63. [Persian].

Bagheri L, Faramarzi M. The effect of 8 weeks of combined training on the ratio of growth hormone to insulin-like growth factor in a serum of elderly women. Sport and Exercise Physiology 2015;8: 1249-56.[Persian].

Nam SY, Lee EJ, Kim KR, Cha BS, Song YD, Lim SK, et al. Effect of obesity on total and free insulin-like growth factor (IGF)-1, and their relationship to IGF-binding protein (BP)-1, IGFBP-2, IGFBP-3, insulin, and growth hormone. Int J Obes Relat Metab Disord 1997;21:355-9. doi: 10.1038/sj.ijo.0800412

Asghari F, Tofighi A, Seyyed mardani SM. Impact of aquatic training on immunity responses of CRP and C3, C4 complement proteins in patients with rheumatoid arthritis. RJMS 2017;23:21-30. [Persian].

Ebrahimi AA, Nikniaz Z, Ostadrahimi A, Mahdavi R, Nikniaz L. The effect of Elaeagnus angustifolia L. whole fruit and medulla powder on women with osteoarthritis of the knee: A randomized controlled clinical trial. European Journal of Integrative Medicine 2014;6:672-9. doi: 10.1016/j.eujim.2014.07.016

Mirazi N, Hosseini A. Effects of hydroethanolic extract of Elaeagnus angustifolia on pentylenetetrazole induced seizure in male mice. Med J Tabriz Uni Med Sciences Health Services 2014;36:74-81.[Persian].

Selvin E, Paynter NP, Erlinger TP. The effect of weight loss on C-reactive protein: a systematic review. Archives of Internal Medicine 2007;167:31-9. doi: 10.1001/archinte.167.1.31

Shamsuzzaman AS, Winnicki M, Wolk R, Svatikova A, Phillips BG, Davison DE, et al. Independent association between plasma leptin and C-reactive protein in healthy humans. Circulation 2004;109:2181-5. doi: 10.1161/01.cir.0000127960.28627.75

McLaughlin T, Abbasi F, Lamendola C, Liang L, Reaven G, Schaaf P, et al. Differentiation between obesity and insulin resistance in the association with C-reactive protein. Circulation 2002;106:2908-12. doi: 10.1161/01.cir.0000041046.32962.86

Namazi A, Aghaalinejad H, Peeri M, Rahbarizadeh F. The effects of short term circuit resistance training on serum homocysteine and CRP concentrations in active and inactive females. Iranian Journal of Endocrinology and Metabolism 2010;12:169-201.[Persian].

Scrutinio D, Bellotto F, Lagioia R, Passantino A. Physical activity for coronary heart disease: cardioprotective mechanisms and effects on prognosis. Monaldi Arch Chest Dis 2005;64:7787. doi: 10.4081/monaldi.2005.591

Bermon S, Ferrari P, Bernard P, Altare S, Dolisi C. Responses of total and free insulin–like growth factor-1 and insulin- like growth factor binding protein-3 after résistance exercise and training in elderly subjects. Acta Physiol Scand 1999;165:51-6. doi: 10.1046/j.1365-201x.1999.00471.x

Berg U, Bang P. Exercise and circulating insulin-like growth factor I. Hormone Research in Paediatrics 2004;62:50-8. doi: 10.1159/000080759

- Delafontaine P, Song YH, Li Y. Expression, regulation, and function of IGF-1, IGF-1R, and IGF-1 binding proteins in blood vessels. Arteriosclerosis, Thrombosis, and Vascular Biology 2004; 24:435-44. doi: 10.1161/01.atv.0000105902.89459.09

Goldspink G. Mechanical signals, IGF-I gene splicing, and muscle adaptation. Physiology 2005;20.p.232-8. doi: 10.1152/physiol.00004.2005

Poehlman ET, Copeland KC. Influence of physical activity on insulin-like growth factor-l in healthy younger and older men. J Clin Endocrinol Metab 1990;71:1468-73. doi: 10.1210/jcem-71-6-1468

Manetta J, Brun JF, Maimoun L, Fedou C, Prefaut C, Mercier J. The effects of intensive training on insulin- like growth factor I (IGF-1) and IGF binding proteins 1 and 3 in competitive cyclists: relationships with glucose disposal. J Sports Sci 2003;21:147-54. doi: 10.1080/0264041031000070895

Rosendal L, Langberg H, Flyvbjerg A, Frystyk J, Orskov Ho, Kjar M. Physical capacity influences the response of insulin –like growth factor and its binding proteins to training. J Appl Physiol 2002;93: 1669-75. doi: 10.1152/japplphysiol.00145.2002

Afzali K, Hosseini- Vashan S.J, Afzali N. Effects of different levels of Elaeagnus angustifolia with and without enzyme on the growth performance, immune system and blood metabolites of broiler chicken. Animal Science Journal 2016;111:147-62.[Persian]. doi: 10.22092/asj.2016.106965

MB. Performance evaluation tests: USA: Peak Performance; 2005. doi: 10.1016/S0166-5316(05)00009-X

Vanaky B, Sadeghi H, Piri M, Ramezani N. the effect of weight bearing water aerobic exercise on the bone density of the lumbar spine of 50-70 years old overweight women. cientific journal of rehabilitation medicine 2014;46.46-52.[Persian].

Calabró P, Willerson JT, Yeh ET. Inflammatory cytokines stimulated C-reactive protein production by human coronary artery smooth muscle cells. Circulation 2003;108:1930-2. doi: 10.1161/01.cir.0000096055.62724.c5

Gabay, C., Kushner, I. Acute-phase proteins and other systemic responses to inflammation. New England Journal of Medicine 1999;340:448-54. doi: 10.1056/nejm199902113400607

Van den Burg PJM, Hospers JEH, Mosterd WL, Bouma BN, Huisveld IA. Aging, physical conditioning, and exercise-induced changes in hemostatic factors and reaction products. Journal of Applied Physiology 2000,88:1558-64. doi: 10.1152/jappl.2000.88.5.1558

Meier-Ewert HK, Ridker PM, Rifai N, Price N, Dinges DF, Mullington JM. Absence of diurnal variation of C-reactive protein concentrations in healthy human subjects. Clinical Chemistry 2001;47:426-30.

Mohammadnia Z, Hassani A. Effects of eight weeks aerobic exercise with consumption of nettle extract on hs-CRP in inactive middle-aged women with type II diabetes. Koomesh 2017;19:56-63. [Persian].

Khakirizi ME As, Mosharaf FT. Investigation of physicochemical compositions of Elaeagnus Angustifolia l fruit for using in food industry. Journal of Herbal Drugs 2012;3:15-20.[Persian].

Tamtaji OR, Talaei SA, Takhtefiroozeh SM, Hamidi GA, Taghizadeh M. Evaluating the analgesic effect of the aqueous extract of Elaeagnus angustifolia in rats. Feyz 2014;18:308-16.[Persian].

Vilarrasa N, Vendrell J, Sánchez‐Santos R, Broch M, Megia A, Masdevall C, Aranda H. Effect of weight loss induced by gastric bypass on proinflammatory interleukin‐18, soluble tumour necrosis factor‐α receptors, C‐reactive protein and adiponectin in morbidly obese patients. Clinical Endocrinology 2007;67:679-86. doi: 10.1111/j.1365-2265.2007.02945.x

Downloads

Additional Files

Published

2023-11-27

Issue

Section

Original Article(s)

How to Cite

The Effect of Eight Weeks of Water Exercise with Supplementation Elaeagnus Angustifolia on Some Inflammatory and Growth Factors in Overweight Postmenopausal Women. (2023). Knowledge and Health in Basic Medical Sciences, 18(1), Page:1-8. https://doi.org/10.22100/jkh.v18i1.2619

Most read articles by the same author(s)

<< < 33 34 35 36 37 38 39 40 41 42 > >>