Clinical and Laboratory Characteristics of Patients with Hypertension Admitted to Baharloo Hospital in Tehran with a Diagnosis of COVID-19 and Its Association with Mortality in 2020

Abstract

Introduction: This study aimed to evaluate patients' clinical and laboratory characteristics with hypertension with the diagnosis of Covid-19 and its association with mortality.

Methods: This retrospective cohort study was performed on 341 patients with hypertension and Covid-19 admitted to Baharloo Hospital. Patient information was collected from patients themselves and medical records during hospitalization. Patients' informed consent was one of the conditions for patients to enter this study. The significance level for all analyzes was considered 5%.

Results: Based on this study's results, the mortality rate of these patients was 22%. The two groups of recovered and dead patients were significantly different in terms of age, oxygen level at admission, and admission to the ICU. The recovered and dead groups were different in terms of white blood cell count (WBC), lymphocyte, neutrophil, inflammatory reactive protein (CRP), blood urea nitrogen (BUN), blood creatinine (CR), and lactate dehydrogenase (LDH). The difference was that the deceased had fewer lymphocytes and neutrophils and more CRP, WBC, BUN, CR, and LDH than the survivors.

Conclusion: Based on the results of this study, patients with hypertension have a higher mortality rate. The deceased differed from the surviving group in terms of white blood cell count, lymphocyte, neutrophil, inflammatory reactive protein, blood urea nitrogen, blood creatinine, and lactate dehydrogenase.