Cardiogenetics: Genetics for Cardiologists
Authors
-
Bahareh Rabbani
- Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.
http://orcid.org/0000-0003-1083-1660
- Shiva Esmaeili - Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.
-
Bahman Akbari*
- Dept of Medical Biotechnology, School of Medicine, Kermanshah University of Medical Sciences, Kermanshah, Iran. - Cardiovascular Research Center, Imam Ali Hospital, Kermanshah University of Medical Sciences, Kermanshah, Iran.
http://orcid.org/0000-0003-4389-7885
-
Nejat Mahdieh *
- Growth and Development Research Center, Tehran University of Medical Sciences, Tehran, Iran.- Cardiogenetic Research Center, Rajaie Cardiovascular Medical and Research Center, Iran University of Medical Sciences, Tehran, Iran.
http://orcid.org/0000-0002-8614-1538
DOI:
https://doi.org/10.22100/jkh.v17i2.2724Abstract
Cardiovascular disease (CVD) is the leading cause of death worldwide, accounting for more than 17.9 million deaths a year. Various factors are involved in the disease's development, including lifestyle, nutrition, environment, and genetic factors. Genetics is one of the main causes of CVD because of the familial accumulation of these diseases especially in countries with traditional cultures. As a result, cardiologists need to be aware of the genetic background of CVD and how to use genetic testing to diagnose and find therapeutic solutions. Here, the genetic basis of various CVDs, especially those with single-gene inheritance, diagnostic methods, and advanced genetic diagnostic techniques are reviewed. Also, for each disease, candidate genes, and molecular genetic techniques appropriately to diagnose are suggested and introduced.
Additional Files
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.
