Treatment of Diabetic Foot Ulcer with Propolis and Olive Oil: A Case Report
DOI:
https://doi.org/10.22100/jkh.v6i4.132Keywords:
Diabetic foot ulcer, Propolis, Olive oil.Abstract
Introduction: Diabetic foot ulcers are one of the main health problems in diabetic patients. Nowadays, there are several ways for the treatment of diabetic foot ulcers, but some patients are still forced to amputation. A 45-year-old woman who had been suffering from type 2 diabetes mellitus referred to Diabetes and Glands Clinic with a wound of the big toe, which was caused 3 months ago due to lack of healthy conditions. Her foot ulcer was under treatment with betadine and penicillin, but remained without healing, and therefore, she was referred to a surgeon for amputation. The aim of this study is to report this diabetic foot ulcer treatment with propolis and olive oil.
Methods: When the patient referred to the clinic, she had a foot ulcer with 2 cm² wound size. After her presenting, the use of betadine and penicillin was halted, and treatment with propolis and olive oil began. The patient was advised to wash her ulcer with serum and put topical admixture on the wound and change it every 12 hours.
Results: A week after treatment, ulcer healed completely.
Conclusion: Propolis with olive oil can remedy diabetic foot ulcer
References
Alberti KG, Zimmet PZ. Definition, diagnosis and classification of diabetes mellitus and its-complitions. Part1: diagnosid and classification of diabetes mellitus, provisional report of WHO Consulation. Diabet Med 1998;15(7):539-53.
King H, Aubert RE, Herman WH. Global burden of diabetes, 1995-2025: prevalence, numerical estimates, and projections. Diabetes Care 1998;21(9):1414-31.
Sicree R, Shaw j, Zimmet P. Diabetes and impaired glucose tolerance. In: Delice Gan. Diabetes Atlas.3th edition. International Diabetes Federation 2006; 51
Larijani B, Forouzandeh F. Diabetic foot disorders. Iran J Diabetes and Lipid Disord 2003;2(2):93-103.
Larijani B, Afshari M, Bastan Hagh MH, Pajouhi M, Baradar Jalili R, Moadi M. Prevalence of lower limb amputation in patients with diabetic foot ulcer in Imam Khomeini and Shariati hospitals, 1979-2001. Journal of Medical Council of I.R.I 2005;23(1):25-29.
Larijani B, Afshari M, Darvishzade F, Bastan Hagh MH, Pajouhi M, Baradar Jalili R, et al. Lower limb amputation in patients with diabetic foot ulcer: A 22 year review. MJIRC 2006;8(3):21-24.
Wagner FW. Supplement: algorithms of foot care. In: Levin ME, O Neal LW, editors. The diabetic foot. 3rd ed. St.Louis, MO, CV:Mosby;1983.p.291-302.
Oyibo SO, Jude EB, Tarawneh I, Nguyen HC, Harkless LB, Boulton AJ. A comparison of two diabetic foot ulcer classification systems: the Wagner and the University of Texas wound classification systems. Diabetes Care 2001;24(1):84-8.
Wieman TJ, Smiell JM, Su Y. Efficacy and safety of a topical gel formulation of recombinant human platelet-derived growth factor-BB (becaplermin) in patients with chronic neuropathic diabetic ulcers. A phase III randomized placebo-controlled double-blind study. Diabetes Care 1998;21(5):822-7.
Larijani B, Afshari M, Fadaei M, Pajouhi M, Bastan Hagh MH, Baradar Jalili R. Effect of local epidermal growth factor on wound healing in diabetic foot. Iran J Diabetes and Lipid Disord 2003;18(5):110-107.[Persian].
Tom WL, Peng DH, Allaei A, Hsu D, Hata TR. The effect of short-contact topical tretinoin therapy for foot ulcers in patients with diabetes. Arch Dermatol 2005;141(11):1373-7.
Bahrami A, Kamali K, Ali-Asgharzadeh A, Hossein P, Heshmat R, Khorram Khourshid HR, et al. Clinical application of oral form of ANGIPARS and in combination with topical form as a new treatment for diabetic foot ulcers:A randomized clinical trial. DARU 2008;16(1):41-48
Chana CM, Chana YW, Laub CH, Laub TW, Laub KM, Lamb FC, et al. Influence of an anti-diabetic foot ulcer formula and its component herbs on tissue and systemic glucose homeostasis. J Ethnopharmacol 2007;109(1):10-20
Zahmatkesh M, Rashidi M. Case report of diabetic foot ulcer with topical honey and olive oil. J Medical Plants 2008;36-41.[Persian].
Lotfy M, Badra G, Burham W, Alenzi FQ. Combined use of honey, bee propolis and myrrh in healing a deep, infected wound in a patient with diabetes mellitus. Br J Biomed Sci 2006:63(4):171-173.
Ghisalberti EL. Propolis: review. BeeWorld 1979;60:59-84.
Chena ChR, Shena CT, Wu JJ, Yangb HL, Hsu SL, CMJ Chang. Precipitation of sub-micron particles of 3,5-diprenyl-4hydroxycinnamic acid in Brazilian propolis from supercritical carbon dioxide anti-solvent solutions. J. Supercrit Fluids 2009;50(2):176-182.
Banskota AH, Tezuka YT, Kadota S. Recent-progress-in pharmacological researchofpropolis. Phytother Res 2001;15(7):561-571.
Tosi EA, Re’ E, Ortega ME, Cazzoli AF. Food preservative based on propolis: bacteriostatic activity of propolis polyphenols and flavonoids upon Escherichia coli. Food Chemistry 2007;104(3):1025-1029.
Khalil ML. Biological activity of bee propolis in health and disease. Asian Pac J Cancer Prev 2006;7(1):22-31
Majno G. The healing hand: Man and Wound in the ancient World. Med Hist 1975;20(4):461
Moore OA, Smith LA, Campbell F, Seers K, McQuay HJ, Moore Ra. Systematic review of the use of honeyas a wound dressing. BMC Comp Alt Med 2001;1(1):2-3
Shojaie Fard M, Esmaelzadeh M, Larijani B. Assessment and treatment of diabetic foot ulcer. International Journal of Clinical Practice 2007;61(11):1931-1938.
Downloads
Published
Issue
Section
License
This work is licensed under a Creative Commons Attribution-NonCommercial 4.0 International License.